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What is Ativan?

Ativan is a neurological drug which helps in a quick and short-term treatment of anxiety and stress. In medical terminology, Ativan is recognized as Lorazepam. Lorazepam is amongst the medication class known as Benzodiazepines. Benzodiazepines directly work on the central nervous system. It relaxes the brain by balancing different chemical in the brain.

enzodiazepines produce different effects by magnifying the activity and the efficiency of the neurotransmitters through acting on its receptors. As compared to other Benzodiazepines, Lorazepam is proved to have a high affinity for gamma-aminobutyric acid (GABA).

Ativan Uses:

Ativan is used for the treatment of trouble sleeping, anxiety disorders, active seizers, alcohol withdrawal, for surgery to delay with memory formation, nausea, vomiting, and for severe agitation. Ativan is usually used for other treatment as for acute coronary syndrome because of cocaine use. It could be taken by mouth or also be injected into vein or muscle. It is sometimes used in chemotherapy additionally to drugs used to treat vomiting and nausea. Ativan is also used as an auxiliary treatment for cyclic vomiting syndrome.

The Dosage of Ativan:

Ativan tablets come in different doses as 0.5mg, 1mg, and 2mg.  The proper dosage of Ativan can only be measured by the consultancy of a specialist. Almost all the specialists recommend that 5mg-6mg per day dosage of this medication is enough for everyone. Any overdose includes severe side effects such as slurred speech, confusion, thought deceleration, respiratory depression, delusions, and coma or death. Benzodiazepines overdoses are treated with flumazenil, a GABA antagonist. But, care is always a supportive cure.

Dangerous interactions:

While many medications are safe but they can become unsafe and hazardous or even life-threatening when used with other drugs. Certain combinations could be safe when in low potency. It can be hazardous to use benzodiazepines with stimulants as a result of the risk of intoxication.  Consumption of alcohol with benzodiazepines can cause respiratory depressions and can lead to unanticipated damage of consciousness at high doses. Always make sure before using that combination of two or more drugs is safe by consulting a specialist.

Precautions:

Ativan should not take with:

  • Severe respiratory failure: (May depress CNS respiratory drive and can indicate acute respiratory failure).
  • Allergy or hypersensitivity: (Allergy or hypersensitivity to lorazepam, or to any benzodiazepine, or to any of the elements in lorazepam drugs or injections).
  • Ataxia (Clumsy and Unsteady gesture of the limbs and chest because of failure of gross muscle motion coordination)
  • Acute intoxication (Lorazepam might interact synergistically with the alcohol effects, narcotics, or other psychoactive substances)
  • Pregnancy and breastfeeding
  • Sleep apnea
  • Acute narrow-angle glaucoma

Physical Effects:

  • Sedation
  • Seizures suppression
  • Muscle relaxation
  • Frequent urination
  • Respiratory depression
  • Nausea suppression
  • Dizziness

Cognitive Effects:

There can different cognitive effects of lorazepam which gradually increase according to the doses. The most common cognitive effects of this drug include:

  • Anxiety suppression
  • Compulsive redosing
  • Amnesia
  • Thought deceleration
  • Dream potentiation
  • Information processing suppression
  • Disinhibition
  • Emotion suppression: (Dull other emotions)
  • Delusions of sobriety (severe cognitive weakening and an incapability to abundantly communicate with others)

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